Patient with the following disease: Hemophilia

Patient with the following disease: Hemophilia
Select one of the following patient factors: genetics, gender, ethnicity, age, or behavior.
Reflect on how that factor might impact your selected disorder, as well as potential
associated alterations and symptoms.
Think about the pathophysiology of the associated alterations, including the normal and
altered cellular function. Consider both intra- and extra-cellular changes that occur.
Post on or before Day 3 a brief description of a patient scenario involving the disorder
HEMOPHILIA and factor you selected. Explain how the factor might impact the disorder
you selected, as well as potential associated alterations and symptoms. Finally, explain the
pathophysiology of the associated alterations including changes in cellular function.

Factors That Influence Disease

Different risk factors such as age, ethnicity, gender, genetics, and behavior among others
influence different diseases. Hemophilia is one of such diseases also influenced by these factors.
The paper delineates on genders as one of the factors that influence hemophilia.
Hemophilia is a condition /disorder that slow the process of blood clotting. Patients with
the disorder therefore, experience prolonged bleeding in case of an injury or even during a
prolonged trauma (NIH, 2014). Serious complication leads to severe bleeding in internal organs,
brain, and joint muscles.
This disease is mostly likely to be experienced by male compared to female. The reasons
why men have higher chances is because they have one X chromosome compared to female that
have two. Defective gene is therefore guaranteed to manifest in men as they carry it. Women
have two X-chromosomes and this reduces the chances of them having two defective copies of
the gene (NIH, 2014). Female are asymptomatic carriers and it is a unusual for them to suffer
from this condition. However, in rare cases, women may suffer from hemophilia when the
mother as well the father carries the gene.

There are alterations in the individuals that suffer from this disease as the blood plasma
clotting factors are reduced requiring to match the coagulation factors for blood clotting (NIH,
2014).The cellular alterations and missing coagulation factors hinders formation of fibrin
necessary for blood clotting causing this severe bleeding. This happens in both genders as long
as an individual is suffering from the condition.
In conclusion, hemophilia is a condition that can be severe if not well treated. As
discussed, it is predominant among males compared to the females because of the x-
chromosomes. Chances of a defective gene among male is higher than among women hence this



NIH. (2014). Hemophilia.

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